Design and Fabrication of a Dielectrophoretic Cell Trap Array

Design and Fabrication of a Dielectrophoretic Cell Trap Array

Volume 2, Issue 1, Page No 84-89, 2017

Author’s Name: Logeeshan Velmanickam, Dharmakeerthi Nawarathnaa)

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Department of Electrical and Computer Engineering, North Dakota State University, Fargo, ND, 58102-6050

a)Author to whom correspondence should be addressed. E-mail: dharmakeerthi.nawara@ndsu.edu

Adv. Sci. Technol. Eng. Syst. J. 2(1), 84-89 (2017); a DOI: 10.25046/aj020110

Keywords: Dielectrophoresis, Cell isolation, Electrode cell trap array, Electric field gradient

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We present a design and fabrication of an integrated micro-fabricated dielectrophoretic (DEP) cell trap array in a microfluidic channel. The cell trap array is capable of isolating target cells in high-throughput manner and producing cell clusters of tunable cell numbers. In this work, we have used commercially available polystyrene beads to show the concept. Bead clusters of various sizes were successfully produced using DEP force (attractive or repulsive). We have found that the number of beads in a cluster depends on the frequency of electric field and the concentration of beads in the mixture.

Received: 01 December 2016, Accepted: 08 January 2017, Published Online: 28 January 2017

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